Can RAPAFLO be used safely with PDE-5 inhibitors?
In a study in 24 healthy subjects aged 45 to 78 years who were taking RAPAFLO with tadalafil or sildenafil at maximum doses, there were no events of symptomatic orthostasis or dizziness. Patients taking RAPAFLO with a single maximum dose of sildenafil (Viagra 100 mg) or tadalafil (Cialis 20 mg) did not experience any clinically meaningful decreases in blood pressure.