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Can propylene glycol have negative health effects when consuming it over a long period/time in small amounts?

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Can propylene glycol have negative health effects when consuming it over a long period/time in small amounts?

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Propylene glycol has been used safely for more than 50 years in a large variety of applications. Studies have shown that propylene glycol has a very low degree of toxicity. No negative health effects from exposure to small amounts of propylene glycol have ever been observed. The authorities have approved the use of propylene glycol in sensitive applications such as in pharmaceuticals, food and cosmetics, and thus confirm its safety.

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