Can PHN be prevented?
Currently, PHN cannot be prevented in all patients. However, prompt medical treatment for shingles can lessen the duration of shingles and lower the risk for PHN. Specifically, the effectiveness of antiviral medication (acyclovir, famciclovir or valaciclovir) is well established if it is taken within 72 hours after the appearance of the shingles rash. There is a major study underway The Shingles Prevention Study whose aim is to determine if vaccination can decrease the incidence and/or severity of shingles and its complications in older adults. The study is also trying to determine if vaccination can protect against PHN. The outcome of this study will help scientists determine whether PHN prevention is a valid strategy using this vaccine.