Can people hear Stewie talk?
In the DVD audio commentary for “E. Peterbus Unum” MacFarlane states that adults can understand Stewie, but don’t take him seriously, “sort of like… if a 4-year-old who [could] talk told you to fuck off.” This concept is supported by the other characters often looking at him as he speaks to them, as if to acknowledge him, although paying no mind his often-ungracious addresses, such as calling Lois by her first name (although a few times over the course of the series he has referred to her as “mother”), referring to Peter as “the fat man,” Brian as “dog” or on occasion “Dogbert,” and Chris and Meg as simply “you there.” The other characters also seem to have blocked out Stewie’s odd behavior.