Can other rules be used as warning rules rather than rejection rules?
There’s another type of warning rule that can be used to indicate prospective action instead of run rejection. With very stable analytical systems, it may be advantageous to interpret rules like the 14s and 10x as warning rules because they are quite sensitive to small shifts that occur from run to run, day to day, or reagent lot to reagent lot. If you do this, you also need to define the response that is appropriate for a warning. That may be to perform maintenance before the next run, carefully inspect the analytical system, review system changes, review patient data, etc.
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