Can non-sterile 70% IPA be used to disinfect surfaces other than those in the DCA of the primary engineering controls in the ISO Class 5, 7, and 8 areas?
Yes. The chapter requires that surfaces be cleaned with sterile water for irrigation or injection to remove any soluble residues with low-shedding wipes. This is followed by wiping with a residue-free disinfecting agent (such as sterile 70% IPA), which is allowed to dry before compounding begins. However, the Chapter does not require that the residue-free disinfecting agent be sterile.
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