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Can neomycin be used as a selectable marker for G418?

April 26, 2017g418 Marker neomycin selectable Used

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Can neomycin be used as a selectable marker for G418?

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Yes, neomycin can be used as a selectable marker for G418. The kanamycin-neomycin resistance genes (neo or aph) from the bacterial transposons Tn601 and Tn5 encode aminoglycoside phosphotransferases (APH) which confer resistance to the antibiotic G418.