Can my doctor increase my dose of clomiphene citrate so that Ill ovulate more than one egg?
A – Clomiphene citrate (CC) therapy is one infertility treatment option at our Sacramento-area practice. CC is a very effective fertility medication for stimulating the ovary to ovulate in those patients who are not ovulating regularly. It acts by indirectly stimulating the pituitary (via its anti-estrogen action) to make more follicle stimulating hormone (FSH), which is responsible for stimulating follicular growth and development. When we use CC, we give enough to make a patient have a normal ovulatory cycle. We feel that increasing the dose beyond that point is not helpful in most cases. Increasing the dose rarely increases the number of eggs produced in most patients, and higher doses of CC can result in more severe anti-estrogen effects on the endometrial lining and cervical mucus that may actually interfere with conception.
