Can methocarbamol trigger a temporary state of depression in clinically depressed individuals?
Methocarbamol (Robaxin) is used to treat muscle spasm and pain. The mode of action of this drug is not known, but it is a central nervous system depressant. Due to this, it must be used with caution in combination with alcohol, benzodiazepines and other CNS depressants. While depression is not listed as a side effect, I have seen some patients experience this on Robaxin.