Can metabion help with the design of an antigenic peptide?
Yes! metabion will highlight the most antigenic regions of a protein, thus allowing us to choose the most immunogenic peptides. This help is provided at no additional charge, and it is based on a computer analysis of the protein sequence using algorithms that take into consideration the hydrophobicity and the knowledge of the tri-dimensional conformation of the different amino acid residues. In some cases, it may be better to generate antibodies with a mixture of 2 or 3 different peptides whose sequence is derived from the same protein sequence. Such approach may increase the chance to obtain antibodies able to recognize the intact protein. Just send the amino acid sequence to antibodies@mymetabion.com, and we try our best to propose some promising antigenic peptides. In general, we suggest to use peptides which consist of 11-18 amino acids.
