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Can maternally derived antibodies (MDA) also block immunity to killed vaccines and prevent active immunization with MLV vaccines ?

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Can maternally derived antibodies (MDA) also block immunity to killed vaccines and prevent active immunization with MLV vaccines ?

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A. Yes. MDA can block certain killed vaccines, especially those that require two doses to immunize. With MLV vaccines, two doses are often recommended, particularly in young animals, to be sure one is given beyond the neutralizing period of MDA.

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