Can maternal antibodies in the embryos reduce the titre of the I-2 Newcastle disease vaccine harvest?
No. Avirulent strains of Newcastle disease virus such as V4 and I-2 inoculated into the allantoic cavity are confined in the cavity. They do not cross the allantoic membrane and do not enter the embryo. Maternal antibody is confined to the yolk sac until about 14 days of incubation and then enters the embryo. Virus harvested in allantoic fluid at 14 days will not have been exposed to antibody.
Related Questions
- Can red blood cells from vaccinated donor chickens that have antibodies to Newcastle disease virus be used in the haemagglutination-inhibition test?
- Can you use the same incubator for preparation of vaccine and isolation of Newcastle disease virus from field samples?
- Can maternal antibodies in the embryos reduce the titre of the I-2 Newcastle disease vaccine harvest?
