Can Leptin be Used to Help Lose Weight or Prevent Diabetes?
As it stands, leptin is still a mysterious hormone that researchers are trying to sort out. To put it simply, though, overweight people tend to have very low levels of leptin in their systems (they may have disruptions in leptin signaling or they may be leptin-resistant, for instance). And, studies have found that feeding leptin to overweight mice causes them to lose weight. This effect was not observed in humans, however. For now, the best way to reduce your chances of diabetes and obesity (and other diseases like heart disease and accelerated aging), according to Rosedale, is to avoid surges in leptin (which can eventually make you leptin-resistant). Eating the typical American diet, full of refined sugars and other processed foods, is a surefire way to cause surges in leptin. Focusing your diet on simple, mostly unprocessed foods like vegetables is currently the best way to reduce surges in leptin and leptin-resistance, Rosedale says. So for now there is no magic leptin injection or
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