Can laser treatments help reduce skin folds from PXE?
There are two broad categories of laser treatment to smooth out the skin. One is the use of the laser to resurface the skin, in which superficial layers of skin are removed and the skin regenerates from hair follicles and sweat glands. The other is non-ablative resurfacing technique which tightens skin by changing the collagen in the dermis. None have been effective in correcting skin laxity in PXE, although there is no published experience on these techniques in PXE. However, the effects in PXE are in the deeper and middle regions of the dermis, making resurfacing impractical.
