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CAN I USE SOME ALTERNATIVE PROTOCOLS FOR STRIPPING OF COMBIMATRIX MICROARRAYS?

April 26, 2017alternative combimatrix microarrays protocols stripping

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CAN I USE SOME ALTERNATIVE PROTOCOLS FOR STRIPPING OF COMBIMATRIX MICROARRAYS?

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CombiMatrix tried several alternative protocols, all of them provided insufficient stripping of targets. Even in the cases when no hybridization signal could be observed after stripping, some residual nucleic acid hybrids remained on microarrays and adversely affected the results of subsequent re-hybridizations. Thus, usage of the recommended protocol with the CustomArray™ Stripping Kit is the only means to preserve integrity of CombiMatrix microarrays.