Can I use NimbleGen ChIP-chip to map DNase I hypersensitive sites?
Yes, NimbleGen ChIP-chip arrays can be used to map DNase I hypersensitive sites. A manuscript by Crawford et al. (2006. Nature Methods. 3:503-509) describes the use of NimbleGen tiled arrays to map hypersensitive sites. Other manuscripts mapping hypersensitive sites using NimbleGen arrays include Sabo et al. (2006. Nature Methods. 3:511-518) and Follows et al. (2006. Genome Research. 16:1310-1319).