Can I use GastroPlus to predict the PK response in a pediatric population?
Yes! The PEAR Physiology (Population Estimates for Age Related Physiology) feature in GastroPlus includes scaling of physiological parameters to a pediatric population. This feature allows you to quickly create the physiology for a child of a defined age and gender. You can also run Virtual Trials to estimate the variability in PK/PD responses in specific pediatric populations.