Can I look at LOH or copy number using the Illumina System?
Yes, any of the Genome Wide Association products can used to look at LOH and copy number using Illumina’s GenomeStudio Genotyping Module. We do not do this analysis for you. If you would like to look at the data in this manner, you must purchase GenomeStudio from Illumina. To do so, please contact your project manager. A GenomeStudio license is available for internal JHU customers only. External customers should contact Illumina directly. • Does your lab provide bisulfite conversion for methlyation studies? No. Each investigator must carry out their own bisulfite conversion. At this time, Illumina recommends the use of the Zymo EZ-DNA Methylation kit for the conversion process Bisulfited DNA is single stranded and unstable, so please be sure to arrange a slot in the SNP Center lab with your project manager before beginning the process. • What is the difference between Golden Gate and Infinium chemistry? For detailed information on the different chemistries, please see Illumina’s websit
