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Can I expect a more predictable retention time with Silica-C columns?

April 26, 2017columns expect predictable retention silica-c time

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Can I expect a more predictable retention time with Silica-C columns?

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[top] Yes, if you develop a method that is optimized with the Cogent Silica-C columns compared with an ordinary silica column, the retention times are generally much more reproducible. The reason is most likely that when using ordinary silica columns the uptake of water changes from run to run and the retention often changes. Since the Silica-C column does not take up water, this phenomena does not take place.