Can I be confident converting my adult patients to monotherapy with LAMICTAL from carbamazepine, phenytoin, phenobarbital, primidone, or valproate as the single AED?
A. The Expert Consensus Opinion for the Treatment of Epilepsy, published in 2005 in Epilepsy & Behavior, reported the results of a survey taken among 51 leading physicians treating epilepsy (43 of 48 responded).1 The survey was designed to address key decision points in the management of epilepsy and seizures. Participants were asked to rank the order in which they would recommend certain therapies and to rate those choices using a 9-point scale. The Expert Consensus Guideline Series: Treatment of Epilepsy was sponsored by unrestricted educational grants from Abbott Laboratories, GlaxoSmithKline, Novartis Pharmaceuticals and UCB Pharma, Inc. The opinions expressed in this survey are those of the expert panel. Dosages, indications, and methods of use referred to in the guideline may reflect the clinical experience of the editors, professional literature, or other clinical sources. When asked which monotherapy they would choose after the failure of initial monotherapy, 91% of the respond
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