Can HupA be used to support mental clarity and cognitive function in the absence of dementia or AD?
Yes. Purfied HupA is marked by a long track record of clinical efficacy and safety in conjunction with a spectrum of desirable neuroprotective and antioxidant effects. Furthermore, HupA has been demonstrated in vitro and in vivo to 1) possess anti-excitotoxic and anti-apoptotic effects, protecting nerve cells from tissue damage, 2) inhibit glutamate neurotoxity, an effect not seen with donepezil or tacrine, 3) exert an antioxidant effect by protecting against hydrogen peroxide induced apoptosis in PC12 cells, 4) reduce hippocampal oxidative damage in aging rats, and 5) protect against amyloid toxicity.
