Can HHT skip generations?
No, but sometimes it can look like it did. At the genetic level, you either have HHT or you don’t. There is no such thing as being a carrier of HHT (that term is reserved for genetic disorders that are recessive, not dominant like HHT.). If a grandparent and grandchild both have HHT, it can safely be assumed that the “parent” in between the two also has HHT. However, remember that HHT can be EXTREMELY variable in its severity even within the same family. For example, some people with HHT get multiple nosebleeds per day and some only a couple per year. So occasionally it might look like HHT skipped a generation because the parent had such mild manifestations of HHT that they were not obvious.
