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Can fluoxetine (as a monotherapy) cause serum creatine levels to rise to 41,000?

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Can fluoxetine (as a monotherapy) cause serum creatine levels to rise to 41,000?

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We found no studies or reports, in the TRIP and Medline databases, of serum creatine kinase levels rising to 41,000 IU/L. References 1. SPC for oxacin 20mg capsules. Last updated February 2004. (http://emc.medicines.org.uk/emc/industry/default.asp?page=displaydoc.asp&documentid=13431). 2. Chechani V. Serotonin syndrome presenting as hypotonic coma and apnea: potentially fatal complications of selective serotonin receptor inhibitor therapy. Crit Care Med. 2002 Feb;30(2):473-6. (http://www.hubmed.org/display.cgi?uids=11889332). 3. Nice guideline on the management of depression in primary and secondary care. 2004. (http://www.nice.org.uk/pdf/CG023NICEguideline.pdf). 4. PRODIGY. Depression. Last revised November 2005. (http://www.prodigy.nhs.uk/depression/0. 5. NPS Limited (Australia). NPS News 35. August 2004. (http://www.nps.org.au/site.php?content=/html/news.php&news=/resources/NPS_News/news35).

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