Can endosonographers evaluate on-site cytologic adequacy?
Savoy AD; Raimondo M; Woodward TA; Noh K; Pungpapong S; Jones AD; Crook J; Wallace MB Division of Gastroenterology and Hepatology, Department of Pathology, Biostatistics Unit, Mayo Clinic, Jacksonville, Florida 32224, USA. BACKGROUND: On-site determination of cytologic adequacy increases the accuracy of EUS-guided FNA (EUS-FNA); however, on-site cytotechnologists are not available to all endosonographers. We hypothesize that experienced endosonographers can accurately assess whether an on-site FNA specimen is adequate. OBJECTIVE: To determine the accuracy of on-site cytopathology interpretation of EUS-FNA specimens by comparing endosonographers with a cytotechnologist. DESIGN: Prospective double-blind controlled trial. SETTING: Academic medical center with a high-volume EUS practice. PATIENTS: Consecutive patients undergoing EUS-FNA of lymph nodes or pancreas tumors. MAIN OUTCOME MEASUREMENTS: Accuracy, sensitivity, and specificity of 3 endosonographers and 1 cytotechnologist for inter