Can eHiTS work with peptide ligands?
Yes, eHiTS can work with peptide ligands, we see very good results using peptides (we have a pharmaceutical partner that exclusively uses eHiTS for peptides). They have seen very good performance with 8-10 residues, although the more you add the longer the computation will take. eHiTS does not have a limit for the number of rigid fragments, but results will be useless beyond 12 or so fragments.