Can cystatin C be used to estimate GFR?
Some studies have reported estimating equations based on serum levels of cystatin C, either alone or in combination with serum creatinine.17 These equations have variable performance compared to serum creatinine and variable performance among populations. These equations need to be validated in other studies prior to use in clinical practice. In addition, calibration of assays of serum cystatin C will require standardization for routine use of estimating equations using cystatin C.