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Can contamination of micro test tubes by bacterial endotoxin be inactivated by autoclaving?

April 26, 2017autoclaving bacterial contamination endotoxin inactivated Micro Test tubes

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Can contamination of micro test tubes by bacterial endotoxin be inactivated by autoclaving?

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“No. Bacterial endotoxins (lipopolysaccharide, LPS) are very stable and withstand normal autoclaving at 121 °C. To inactivate LPS, the objects have to be baked at 250 °C, which, of course, is not possible with plastics.