Can certain medications cause a person to become anemic?
Yes, medications can cause anemia for many different reasons. For example, chemotherapeutic agents often cause anemia because they the bone marrow’s ability to manufacture red blood cells, hemoglobin is carried by RBC’s, If there are not enough RBC’s, the body does not get the right amount of oxygen. Other types of medication-induced anemia are usually unpredictable, and not well understood (such as drug induced aplastic anemia). Some patients react to drugs because of inherited susceptibility, such as patients with glucose-6-phosphate dehydrogenase (G-6-PD) deficiency. G-6-PD is an important enzyme that buffers the mature red cell against oxidative stress. In individuals who are deficient in G-6-PD, exposure to certain chemicals, drugs, or even some foods will result in the alteration of hemoglobin and breakdown of red blood cells.