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Can cells from allogeneic blood and marrow transplants contribute to the formation of nonhematopoietic tissues?

April 26, 2017Allogeneic blood cells contribute FORMATION marrow tissues transplants

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Can cells from allogeneic blood and marrow transplants contribute to the formation of nonhematopoietic tissues?

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The report by Imanishi and colleagues in this issue of Blood indicates that they do. Using short tandem repeat analysis, these researchers found substantial amounts (9%-72%) of donor DNA occurring in fingernail clippings from 9 of 21 recipients 2 years and more after transplantation.