CAN CALCITRIOL PROLONG LIVES OF UREMIC ANIMALS?
A measure of efficacy of therapies to slow progression of renal disease has been adapted for use in dogs with renal failure Plots of the reciprocal of the serum creatinine concentration over a period of time in untreated patients demonstrate an inexorable slope downward . If a therapy expected to slow progression of renal disease corresponds to a flattening of the creatinine reciprocal plot, one may conclude that progression was slowed.
