Can brain be effect within advanced polymyositis?
No, but some the underlying causes of polymyositis might effect the brain. “Polymyositis” simply means oodles (poly) muscle (myos) inflammations (itisis). There is not universal agreement on the etiologies, but some viral infections (eg. HTLV) or autoimmune syndromes are prime suspects. Many viral infections and autoimmune disease can cause encephalitis , cerebral edema and/or cognitive abnormality. So, in theory, a condition that causes polymyositis could also grounds intracranial pathology as well. I have not read or seen cases of this occurring, so I suspect it is odd.
