Can boosting of immunity through vaccination prevent herpes zoster?
Phase I and II studies involving 400-500 adults over 55 years of age have shown that the vaccine boosts humoral and cellular immunity. A clinical trial, that will ultimately enroll 30,000 adults, is now underway to test a newly formulated varicella vaccine in adults > 55 years of age with a prior history of varicella. Three to five year follow-up will assess both the risk and the severity of herpes zoster in this cohort.
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- Can boosting of immunity through vaccination prevent herpes zoster?
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