Can Biologic Drugs Tackle Antibiotic Resistance?
Posted on: Wednesday, 30 April 2008, 06:00 CDT Antibody-based products present a novel approach to the treatment and prevention of infections, as an alternative to conventional antibiotics. Several companies are developing such agents for a range of indications, but their cost, complex manufacturing methods and mode of administration are restrictive. A high unmet need and well defined target groups are key to commercial success in this market. Increased interest in the development of antibody-based agents Historically, serum-derived antibody therapy has been used to treat a wide range of infections, but safety concerns and the increased availability of anti-infective drugs have led to the slow decline of antibody agents over the past five decades. However, advances in technology have improved manufacturing costs and tolerability, leading to a renewed interest in the development of antibody-based agents for prophylaxis (prevention) and the treatment of infectious diseases. A key factor
