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Can bacteria or fungi grow in a cartridge? And do they influence the binding efficiency and flow rate?

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Can bacteria or fungi grow in a cartridge? And do they influence the binding efficiency and flow rate?

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A23: Cartridges used for several months have been demonstrated to show a slower flow rate. However, this does not effect the binding efficiency of the cartridge. Similarly, the growth of bacteria or fungi inside the cartridge can not be entirely excluded if the cartridge has been used to purify phosphate containing buffers.

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