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Can Azathioprine reconstituted powder for injection (pfi) be administrated orally or through a gastric tube?

April 26, 2017administrated azathioprine Gastric injection orally PFI powder reconstituted tube

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Can Azathioprine reconstituted powder for injection (pfi) be administrated orally or through a gastric tube?

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Azathioprine powder for injection is after reconstitution alkaline with irritating qualities. Precipitation can occur, because azathioprine has low solubility in neutral and acid environments. Therefore it is discouraged to administer azathioprine pfi orally or through a gastric tube. For oral administration, azathioprine tablets are available.