Can Approved Use of Diallyl Disulfide and Related Sulfides Affect Human Health?
Diallyl disulfide and related sulfides are unlikely to affect human health when used according to the label directions. Exposure to diallyl disulfide and related sulfides may occur when handling and applying the product. When assessing health risks, two key factors are considered: • the levels where no health effects occur; and • the levels to which people may be exposed. The dose levels used to assess risks are established to protect the most sensitive human population (for example, children and nursing mothers). Only uses for which the exposure is well below levels that cause no effects in animal testing are considered acceptable for registration. The technical grade active ingredient, diallyl disulfide and related sulfides, is highly acutely toxic by the oral route, slightly acutely toxic by the dermal route, minimally irritating to eyes, severely irritating to skin, a skin sensitizer, not a mutagen, and a respiratory irritant. Due to the toxic and irritative potential of diallyl di
