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Can analytes be extracted from organic solvent using SPME?

April 26, 2017analytes organic solvent spme

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Can analytes be extracted from organic solvent using SPME?

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We do not recommend extraction from organic solvents. However, you may extract analytes using the headspace above polar organic solvents, at the risk of a reduced distribution constant, fiber damage from swelling, and a large solvent peak on your chromatogram.