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Can adult stem cells repair the damage?

April 26, 2017Adult damage Repair stem cells

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Can adult stem cells repair the damage?

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The heart is unable to recover fully from myocardial infarction, the tissue damage caused when blood flow is interrupted. But now Orlic et al. demonstrate that adult haemopoietic stem cells have the potential to repair both the structure and function of the failing heart. Transplantation of bone marrow cells into infarcted tissue in a mouse model of coronary artery disease regenerates dead myocardium, increasing cardiac muscle mass and improving cardiac function. The prospects of regenerative medicine of this type, and other revolutionary techniques are discussed in the News Feature pages. Bone marrow cells regenerate infarcted myocardium DONALD ORLIC, JAN KAJSTURA, STEFANO CHIMENTI, IGOR JAKONIUK, STACIE M. ANDERSON, BAOSHENG LI, JAMES PICKEL, RONALD MCKAY, BERNARDO NADAL-GINARD, DAVID M. BODINE, ANNAROSA LERI & PIERO ANVERSA Nature 410, 701-705 (5 April 2001) | First Paragraph | Full Text | PDF (498 K) | Cardiovascular biology: Hearts and bones MARK SUSSMAN The idea of repairing dama