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Can a new substrate bind to the changed active site of an enzyme during non-competative inhibition?

April 26, 2017active bind Biology changed enzyme Mathematics site Substrate

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Can a new substrate bind to the changed active site of an enzyme during non-competative inhibition?

1 Answer

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10 Posted

Since pure non-competitive inhibition alters only the Vmax for the enzyme, and not the Km, the answer to your question is YES. Substrate can still bind to the active site in the presence of a non-competitive inhibitor.