Can a molecular test enhance the diagnostic efficacy of a cytology sample containing “suspicious” cells?
Work done by Yale clinical investigators has demonstrated that cytological specimens categorized as “suspicious for malignancy” by morphological examination can be classified as either positive or negative by assessing the percentage of cells harboring a mutated allele (Deborah Dillon, M.D., et al. ACTA CYTOLOGICA, 46, no.5 (Sept-Oct 2002): 841-747).
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- I want to know if there are neoplastic cells in a urine sample. What test do I request - urinalysis or cytology?
- Can a molecular test enhance the diagnostic efficacy of a cytology sample containing "suspicious" cells?
