At present, what are the latest medical progresses on climacteric state?
Recently, it has been demonstrated in medical studies that, for the manifestations of climacteric symptoms, shrunk ovaries and decreased estrogen production in climacteric women, the low content of serum estrogen is the basic reason, while the decreased estrogen level will cause the imbalance of Hypothalamus-Pituitary-Ovary Axis, then imbalance of neurotransmitter, hormone and cytokines, etc. will be caused, as well as the immunological imbalance, i.e. the functional abnormality of Neuroendocrine-Immune Network. Therefore, low content of serum estrogen is the major reason of symptoms of climacteric syndrome. It has been observed in clinics that, the serum E2 (estrogen) level decreases in patients during climacteric period, or E2 is seriously insufficient or lacked, and it can not exert its feedback inhibition effect, the follicle stimulating hormone (FSH) and luteinizing hormone (LH) secreted by hypothalamus and pituitary are obviously increased, and the activity of interleukin-2 is si
