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assay also be used for apoptotic CK18‑positive cells from other species?

April 26, 2017apoptotic assay cells species Used

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assay also be used for apoptotic CK18‑positive cells from other species?

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The M30 antibody recognizes caspase‑cleaved cytokeratin 18 (CK18Asp396‑NE M30) from human, rat, mouse and rabbit and can be used for the analysis of apoptosis when the appropriate cell types are used. It is recommended that the presence of CK18 is confirmed for the individual test cell line. In our experience, the M30‑Apoptosense assay shows the highest sensitivity using human samples. Analysis of CK18Asp396‑Ne M30 levels in serum, plasma samples or other body fluids is currently only recommended in the human system.