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Are vitamins C and E or CoQ10 Nrf2 Activators?

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Are vitamins C and E or CoQ10 Nrf2 Activators?

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Vitamin C is not a Nrf2 Activator. Vitamin E and CoQ10 are very, very weak activators at high doses and in cultured cells. It’s not clear if these compounds have practical Nrf2 activating activity in intact animals, or whether sufficiently high concentrations could be reached.

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