Are topical retinoids safe in pregnancy?
Topical retinoids are used to treat acne and sun-damaged skin. These include topical tretinoin (Retin A, Renova), adapalene (Differin) and tazarotene (Tazorac). Small amounts of these drugs may be absorbed through the skin into the bloodstream. Studies suggest that topical retinoids do not cause birth defects (6). However, some questions about their safety remain, due to a few reports of birth defects in babies of women who used these preparations during pregnancy (6). Until more is known about the safety of topical retinoids during pregnancy, its best for women who are pregnant or planning pregnancy to avoid them. back to top Are there other retinoids that are unsafe during pregnancy? All oral retinoids pose a risk of birth defects similar to those caused by isotretinoin and should be avoided during pregnancy. As with isotretinoin, women should have a pregnancy test before starting these drugs and another each month. Women also should use two reliable forms of birth control during tre
