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Are tissue culture products tested for DNase, RNase as well as for endotoxins?

April 26, 2017culture dnase endotoxins products rnase tested tissue

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Are tissue culture products tested for DNase, RNase as well as for endotoxins?

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Yes, all tissue culture products are DNase-and RNase- free and non-pyrogenic. Testing of DNase/RNase is performed by PCR. Even low amounts of contaminants can be detected by this sensitive method. Contingently contaminants with endotoxins are detected by FDA admitted LAL-Tests (Limulus Amobocytes Lysate). The detection limit for this test is >0.06 EU/ml.