Are there warning signs that point to an impending swelling attack?
Many swelling attacks are preceded by warning signs, also known as prodromes. The most well-known precursor is erythema marginatum, which is characterised by patches of erythema (skin reddening) that are non-pruritic (not itchy) and often annular (ring-like) in shape. They precede about 25% of swelling attacks. The subsequent swelling, however, does not always appear at the same site. Further prodromes include tingling in the skin, mood variability as well as anxiety and exhaustion.
