Are there scales of the FACT system that tend not to change much over time?
Yes, depending on the context of the evaluation. For example, the Social Well-Being (SWB) subscale of the FACT-G (the General version) tends not to change much in a clinical trial of a drug therapy for a medical condition. We assess SWB because it is important to people whose feedback has helped build these questionnaires. However, an investigator may opt to avoid using a non-responsive subset of questions as a trial endpoint. This does not mean excluding the subscale from the questionnaire, but rather selecting a score (a subscale score or the Trial Outcome Index) as the outcome endpoint, as the total score should be evaluated and will depend on the inclusion of the SWB subscale.
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