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Are there patients without congenital LQTS who are particularly vulnerable to QT prolongation and torsades de pointes?

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Are there patients without congenital LQTS who are particularly vulnerable to QT prolongation and torsades de pointes?

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Some people with a normal QT interval have extreme sensitivity to drugs that can prolong the QT. They may be silent carriers of genetic mutations for Long QT syndrome. Women tend to have a greater QT prolongation in response to these drugs (see comments on our lists).

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