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Are there gender differences in severity of ankylosing spondylitis?

April 26, 2017ankylosing differences gender severity spondylitis

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Are there gender differences in severity of ankylosing spondylitis?

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Lee W; Reveille JD; Davis JC; Learch TJ; Ward MM; Weisman MH Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. OBJECTIVE: To examine the clinical and radiographic features in men and women in the Prospective Study of Outcomes in Ankylosing Spondylitis cohort, a large well-defined cross-sectional study of patients with AS, in order to understand the influence of gender in determining the severity of ankylosing spondylitis. METHODS: Extensive clinical assessments and spine radiographs were performed in 302 men and 100 women with AS of > or = 20 years duration. Radiographs were scored using the Bath Ankylosing Spondylitis Radiographic Index Spine (BASRI-spine) score (range 2-12). Functional impairment was measured by the Bath Ankylosing Spondylitis Functional Index (BASFI) and the Health Assessment Questionnaire for the Spondyloarthropathies (HAQ-S). RESULTS: Radiographic severity was worse among men. The unadjusted median BASRI-spine score for men was 10,