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Are there differences between adult and pediatric malignant astrocytomas?

April 26, 2017Adult astrocytomas differences malignant pediatric

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Are there differences between adult and pediatric malignant astrocytomas?

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Malignant astrocytomas in children &#062 4 years old display TP53 mutations (50%) and p53 overexpression (77%) similar to adult tumors. Both TP53 mutations (0%) and p53 overexpression (14%) were much lower in children &#060 4 years of age.